Follows the lives of different mothers on Mother's Day. Sandy (Aniston) is happily divorced until she learns that her ex-husband eloped with a much younger woman. Now she must learn to deal with big changes in her life as her two boys now have a stepmom. Sisters Jesse (Hudson) and Gabi (Chalke) get an unexpected surprise from their mother, who is not happy to find out Gabi is a lesbian and Jesse is married to a man of color. Miranda (Roberts) has no kids and is focusing on her career. Kristin (Robertson) is enjoying life as a new mother but feels pressure from her boyfriend to get married. Bradley (Sudeikis) is trying hard to be the best parent for his two girls since their mom passed away last year, but he wants to pretend that Mother's Day doesn't exist.