The movie explores the mystery and origins of the legendary Highway Sheila. Two reporters who hate each other are forced to work together to find out if there is any truth to Highway Sheila causing numerous accidents on the Higginson Highway. Their investigation takes them on a journey, that involves ghost hunting and banishment, having to deal with an egotistic famous musician, and a record manager who has skeletons in his closet. Caught in their investigation is a friend of theirs who thinks that she may be possessed by the spirit of Highway Sheila.