The Wedding Diary 2 picks up two years after the marriage of Wei Jie (Aniu) and Zhixin (Elanne), as they welcome an unexpected new member to their family. But all is not well for Wei Jie's in-laws when Zhixin's father Colin (Jack Choo) suffers a stroke, which puts a strain on the couple's relationship as Zhixin must step up to handle her father's business and also ensure that her mother (Kara Hui) does not fall into depression and anxiety about her husband's condition.