After to have some dreams about a crimes with a similar pattern with the Jack the Ripper's crimes, Sherlock Holmes and Doctor Watson moves to Madrid to investigate the deaths of some women committed in the Ripper's style. In Spain, Watson meets with an old friend, Dr. Delgado, who introduces Holmes and Watson in the high society of the city, knowing important people like compositor Isaac Albéniz, writer Benito Pérez Galdos or the young journalist José (Josito) Alcántara, who follows the assassinations through his reports for La Gaceta, an important Madrid's paper news. Other people include Duquesa de Lima, her niece Elena (a Watson's love interest), and Marqués de Simancas, a businessman with connections with the Ministerio de Fomento (equivalent to Department of Housing and Urban Development) for some construction projects in the city. Meeting Inspector Válcarcel, Holmes, Watson and Alcántara looking for discover if Jack the Ripper is really the murderer.