"Sir" is a convict and a former AIIMS student with an enigmatic history. The movie unfolds the sensational story of his pre-detention life - his secret experiments on eliminating any virus from a human body. It seems he even succeeds in finding the Holy Grail in Virology. What follows thereafter is a series of trials of his vaccine on people - two of them die while the third goes missing after which "Sir" is put behind the bars. A young and curious journalist, Nidhi sets up a date with "Sir". After hearing his story she offers herself as a subject after which the movie ends in a climax.