Pyjama Girls presents the chaotic friendship of Irish teenagers Lauren and Tara as they navigate the trials of life, dressed all the while in their uniform of rebellion: pyjamas. Balancing tenderness with hilarity, Pyjama Girls tracks the explosive micro-dramas of teenage life against the bleak backdrop of Dublin's inner city flats. Lauren's future is uncertain, although she did well in first year, she now finds herself suspended form school for disruptive behaviour. Over the course of the film we learn about the challenges that life throws her - from her addict mother to the disruptive world of the flats - and understand the crucial importance of her friendship with Tara.