Alabama Snake explores the story of Oct. 4, 1991, when a violent crime was reported in the town of Scottsboro, Alabama. Glenn Summerford, a Pentecostal minister, was accused of attempting to murder his wife with a rattlesnake. The details of the investigation and the trial that followed have "haunted Southern Appalachia for decades." Alabama Snake features local historian and folklorist, Thomas Burton, who has spent his life studying the culture, beliefs, and folklore of Pentecostal snake handlers, painting a "Southern Gothic portrait" of Summerford and his tale of demon possession.