Graduating medical student Ramon (Rogelio de la Rosa) fell in love with Pacing (Rosa del Rosario), a strong devotee of the Virgin Mary of Antipolo. Though Ramon is not that religious and seldom goes to church, he courts Pacing, even going to church with her. Pacing gifts Ramon a framed images of the Virgin of Antipolo that will guide him, particularly with his studies. Ramon eventually finishes his medical course, successfully passes the board, and becomes a top-notch surgeon.