In Weedsville, Ontario, friends Royce (an ideas guy) and Dexter (the quiet, introspective one of the two) are slacker druggies. In Dexter owing their drug dealer Omar $1,700, Royce, with the help of his friend Mattie (who many people, including Omar, "mistakenly" believe is a hooker), has made a deal with Omar to sell some of his drugs for him in the profit amount of what Dexter owes as payment. Mattie, who is also a druggie, came up with the idea having a secondary plan in mind to pay back Omar. She is aware that wealthy Jason Taylor, who is currently in the hospital with his wife Irene standing 24-hour vigil there leaving their house empty, does not believe in banks and keeps his money in a safe in the house. As Mattie knows the safe combination, the three of them can steal the money and thus keep Omar's drugs for their own consumption. As the week progresses with the three awaiting the right time to make the heist, Mattie overdoses on the drugs and dies. As Royce believes going to the authorities to report Mattie's death is not an option, he and Dexter have to find a way to dispose of her body. In the process of getting rid of Mattie's body, Royce and Dexter witness a criminal act by a group of Satanic cultists led by Abel, who they knew casually in high school. Following, Royce and Dexter have to evade both the cultists who are after them with Abel proverbially knowing "where they live", and Omar, who Dexter cannot now pay back no longer having the drugs or the combination to the safe.