Several years since Benjamin Franklin Gates (Nicolas Cage) found the Knight's Templar and became rich and famous. Now, another treasure hunter named Mitch Wilkinson (Ed Harris) has found what is a missing page of the diary of John Wilkes Booth, which contains clues to the location of a lost city of gold, Ben must compete against Mitch to find the lost city, he goes to France and Great Britain to find other clues and even peak inside the President's secret book to put the pieces of the puzzle together, his parents and his friends also help Ben find the lost city and to stay one step ahead of Mitch.