Nurse Caroline Ellis quits her job to take care of elderly Ben Devereux who had a stroke and can't talk. When she gets to his house in Terrebonne Parish, Louisiana, she meets Ben's wife Violet, who acts suspicious and creepy. The family's lawyer, Luke Marshall, convinces Caroline to stay. She goes to the attic and finds a secret room there full of spells, hair, and bones used to practice Hoodoo, but Violet says she has never seen this secret room. Caroline wants to help Ben, thinking that Violet has put a spell on him. She knows Hoodoo can't hurt someone who doesn't believe in it. Can Caroline save Ben, or will she end up being the one who needs to be saved?