Under the watchful eye of his mentor Captain Mike Kennedy, probationary firefighter Jack Morrison matures into a seasoned veteran at a Baltimore fire station. Jack has reached a crossroads, however, as the sacrifices he's made have put him in harm's way innumerable times and significantly impacted his relationship with his wife and kids. Responding to the worst blaze in his career, he becomes trapped inside a 20-story building. And as he reflects on his life, now Deputy Chief Kennedy frantically coordinates the effort to save him.