After an outbreak of a mysterious virus, the world is dominated by vampires helped by the traitorous Vichys. The atheist Gwen Waters leaves the small town of St. Anthony on her bicycle, trying to find the alcoholic Priest Joe Cahill and bring him back to her town to give hope to the humans dwelling there. Father Joe rebuilds the church with the support of some locals but is attacked by vampires and Vichys leaded by the evil Father Alberto Palmeri, in a battle between good and evil.