After four of his men have been poisoned by Joe Lang ('Carl Mathews' )qv)), a member of a land-grabbing outlaw gang led secretly by town boss Carson (Leonard Penn), rancher Mark Jones (Steve Clark) beds his herd on Six Gun Mesa just outside of town. Lang stampedes the cattle and Jones and all of his cowhands are killed. Carson implicates and frames ranch foreman Dave Emmett (Riley Hill) for the crimes, and Dave's friends, Johnny Mack (Johnny Mack Brown) and Whiskey Evans (Milburn Morante), set out to prove his innocence.