Shortly after the funny adventure of Sly and Whit in Baby Geniuses (1999), a new batch of intellectual toddlers, Archie, and his friends, Finkleman, Alex, and Rosita, find themselves entangled in a nefarious scheme devised by the powerful media mogul, Bill Biscane. However, this time, the babies have an ally in their battle against evil: the ultra-cool super-hero spy, Kahuna. As he joins forces with the baby-team, a race against the clock begins, to stop villainous Biscane from using his state-of-the-art satellite system to control the minds of the kids all over the world. Can the team of super-baby geniuses save the day?