John Bradley, a mortician lives in a large house with his cold, heartless wife and daughter Susan, where he runs his business . He is unaware that his wife is having an affair with his very own brother and they plot to kill him for life insurance money. His daughter Susan, who has a fascination with tarantulas on the other hand finds out and decides to teach her mother a lesson, which results in her death. Fueled by that incident Susan use her tarantulas to seek vengeance on everyone who is ever wronged her and her father.