With a pending old debt from the past and the genuine threat of losing his badge for good, the tough and gruff San Francisco police officer, Inspector Jack Cates, pushes his luck and turns to his reluctant former partner, Reggie Hammond. Having spent seven long years in jail after the events of 48 Hrs. (1982), Reggie is about to taste the air of freedom, when an attempt on his life drags him into a new circle of violence, as Jack is almost obsessively trying to prove that the elusive criminal mastermind known as the "Iceman" exists. But, this time, the odds are against the mismatched duo. Will Cates clear his name?