Six heterosexual couples (a taxi driver and his wife; a billionaire and his well-known model lover; a retired musician and his maid; two journalists; a ventriloquist and a school teacher, and a young couple in their wedding night) arrive at La Cigarra, a love hotel in Buenos Aires, and end up in quarantine when a French sailor who arrived earlier with a prostitute has brought the bubonic plague to the place, causing all kinds of inconveniences and entanglements among the guests, the personnel and the persons outside, including relatives, friends, pupils and the press.