Congo Bill, a tamer of wild animals, intends to find Ruth Culver, a missing woman who has just inherited the Culver Circus, worth half a million dollars. He has heard of the existence somewhere in Africa of a white queen who might be Ruth. Once on the African continent, Congo Bill's safari gets attacked several times. The man behind all that is none other than Andre Bocar, a trafficker in cahoots with Bernie MacGraw, who hopes to capture the Culver inheritance. With the help of Cameron, a mysterious stranger, Congo Bill manages to locate Lureen, the white queen, who turns out to be Ruth Culver as the tamer had guessed. But trouble is not at an end yet. Indeed Nagu, the witch doctor, who smuggles gold with Bocar, tries to get rid of Congo Bill. To no avail, for Bill and Cameron (who happens to be a colonial officer) recover the gold and capture Bocar. Congo Bill returns to the USA with Lureen/Ruth with a view to creating new circus, even bigger than the former one.