Wacky Waters, the greatest pitcher in baseball, is burning up the league until he meets Pepita Zorita, a bundle of Mexican dynamite from Hollywood. Before long, Wacky can't pitch for thinking of Pepita. The team is on a losing streak. The catcher Hippo Jones, team bachelor Smokey Lee and Marty Samuels, an educated ball player, try coaching, warnings and psychology to distract Wacky's attention away from Pepita but nothing works. The wives of the ballplayers, led by Hazel Jones, devise a plan to get rid of Pepita. They talk banker/owner Updyke into buying the picture rights to "Twenty-one Nights" and sending Pepita back to Hollywood to star in the film. It works as Wacky begins winning his pitching starts again, but Pepita breaks all records for her for finishing a film and heads back. The wives fly to Kansas City, meet Pepita with a baseball bat and other kidnapping tools and Pepita wakes up in a bathroom on the 22nd story of a hotel tied and gagged with two guardians. After fights with everyone ranging from the house detective to a Civil War veteran, Pepita escapes and heads east where the team is in the seventh-and-deciding game of the World Series with Wacky on the mound.