In London, sculptor Ivan Igor struggles in vain to prevent his partner Worth from burning his wax museum...and his 'children.' Years later, Igor starts a new museum in New York, but his maimed hands confine him to directing lesser artists. People begin disappearing (including a corpse from the morgue); Igor takes a sinister interest in Charlotte Duncan, fiancée of his assistant Ralph, but arouses the suspicions of Charlotte's roommate, wisecracking reporter Florence.